Clemson Tigers vs. Louisville Cardinals Betting Odds - Free Pick

Date/Time: 3:30 PM EST Saturday September 16, 2017
Location: Papa John's Cardinal Stadium Louisville, KY

Betting Odds

Spread: Clemson -3
O/U: 56

No. 3 Clemson Tigers vs. No. 14 Louisville Cardinals on 9/16/2017 at 8 PM at Papa John's Cardinal Stadium Louisville, KY. The linesmaker has Clemson as a 3-point spread favorite with a total of 56.

Clemson is 2-0 ATS with an O/U record of 1-1 and Louisville is 1-1 ATS with an O/U record of 1-1.

Last Games: Clemson moved to 2-0 on the season with a 14-6 win over Auburn where they covered the 6-point spread and the total going Under. Louisville moved to 2-0 on the season with a 47-35 win over North Carolina where they covered the 11.5-point spread and the total going Over.

Last season at Louisville the Tigers beat the Cardinals 42-36.

This season Clemson is 2-0 at home and Louisville is 0-0 on the road.

Clemson ranks 36th in total offense and 2nd in total defense while Louisville ranks 5th in total offense and 72nd in total defense.

Sagarin Rankings

Clemson: 92.75
Louisville: 84.37
Injuries CLEMSON
  • [CB] 09/10/2017 - Marcus Edmond left last game, "?" Saturday vs. Louisville ( Foot )
  • [S] 09/10/2017 - Van Smith "?" Saturday vs. Louisville ( Knee )
  • [QB] 09/08/2017 - Tucker Israel out indefinitely ( Illness )
  • [DE] 08/23/2017 - Richard Yeargin out for season ( Neck )
  • [S] 08/16/2017 - P.J. Blue out indefinitely ( Knee )
  • [WR] 08/29/2017 - Devante Peete out for season ( Knee )
  • [RB] 09/11/2017 - Jeremy Smith out for season ( Lower Body )
  • [CB] 09/10/2017 - Jaire Alexander "?" Saturday vs. Clemson ( Leg )

Clemson at Louisville Trends/Angles

  • CLEM is 4-0 ATS in their last 4 games overall
  • CLEM is 1-5 ATS in their last 6 conference games
  • CLEM has an Over record of 5-0 in their last 5 road games
  • LV is 1-4 ATS in their last 5 home games
  • LV is 1-5 ATS in their last 6 games overall
  • LV has an Over record of 9-3 in their last 12 conference games
Next Game Clemson vs. Boston College
Louisville vs. Kent State


We feel that the Cardinals can win this game outright making the points a bonus.

Game Pick: Take Lousiville +3 at Bovada and get a big bonus up to $250 FREE on your first deposit!



NFL Preseason: Contrary to popular belief, NFL pre-season bets are some of the easiest football wagers to cash in on! Some coaches actually divulge their game plan prior to the game! Smash your bookie in the mouth by coat tailing our plays!

NFL Underdog of the Week: Each week's NFL card usually presents 2-3 barking dogs. We sort through the mix to produce the best NFL underdog pick of the week!

NFL Best Bet: The crown jewel of our football predictions! Find out who our seasoned pros like as their top pick in this week's action!

Newsletters Signup

Sign up for our newsletter to get free picks and special offers.